Patriarch of Antioch (d. 518), was chosen by the emperor Anastasius I to succeed Palladius, most probably in 498.

He endeavored to please both parties (Orthodox & Chalcedonian) by steering a middle course in reference to the Chalcedon decrees, but was induced to agree to the request of Anastasius that he should accept the Henoticon, or decree of union, issued by the emperor Zeno. Afterward he was against it by accepting Nestorian faith, A synod was convened in Sidon in 512 by the eighty of orthodox bishops, which resulted in Flavian being replaced by St. Severius. Flavian was then banished to Petra, where he died in 518.

Flavian was soon canonized by the Roman Catholic Church. In the Roman Martyrology his feast is entered July 4th.