Ignatius II Patriarch of Antioch (878-883), he is monk Yeshu, studied and became a monk at the Monastery of Harbaz. After departure of John III, the Holy See of Antioch was vacant from 873 till 878. Metropolitans of the Syriac church met at Mor Zakai (Zakka) Monastery near Al-Raqqa, Syria, and elected the monk Yeshu to be a patriarch of Antioch, the Synod called him and consecrated him patriarch of Antioch on June 05, 878.

In the same Synod which met to consecrate him at the Monastery of Mor Zacchaeus, he issued twelve canons and made them public to the congregation through a Patriarchal Bull. There is a copy of these canons at the Patriarchate of Antioch, except for the first and the second canons and part of the third.

He ordained twenty-six metropolitans and bishops and died in 883.